Time suitable to take antihypertensive

Researchers compared morning and evening BP-lowering medications. Research results shows that the evening use of antihypertensive leads a much lower night BP and a better maintenance of the diurnal rhythm. The study included 720 hypertensive patients.

They used amlodipine etc. for 12 weeks. Researchers divided the subjects into two use groups, one between 6:00 and 10:00, and the other between 18:00 and 22:00. Compared with the morning group, systolic and diastolic blood pressures were lower than 3 mm Hg and 1.4 mm Hg, respectively, in subjects in the evening group.

Researchers concluded that the use of antihypertensive before sleeping could lead to a well-controlled night BP and improved diurnal rhythm, while the effect of the mean BP did not decrease and the risk of developing hypertension did not increase.